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Somente 1 a 4% de uma dose oral da droga aparece nas fezes de forma inalterada ou como metabólito.

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W zależności od producenta lek jest dostępny w dawkach: 2,5 mg, 5 mg, 10 mg i 20 mg. TCAs are potent inhibitors of serotonin and norepinephrine reuptake!

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About the book


Sue set sail from England, aged 7, with her parents and younger brother on a dream ocean voyage in the wake of Captain Cook to reach the palm trees, beaches and limitless seafood of the South Pacific, which turned into a 10 year fight through storms, shipwrecks, reefs and limited schooling to break away and get back home.

This is Sue’s story of that trip.  Within a year of setting sail she was injured in a devastating shipwreck in the Indian Ocean and, once recovered, educated herself by post.  Most challenging of all she had to find a way to grow up while being contained with her family in a small space floating around the Pacific Ocean. 


…ambition leads me not only farther than any other man has been before me, but as far as I think it possible for man to go.

The Journals of Captain Cook: The Voyage of the Resolution and Adventure.


It is a simply extraordinary story, outrageous in its breaking all the rules – in 30 years in schools, the most extreme absence I encountered was a family who took their children away for one term for a reasonably safe hike through South America. Fabulous I thought – most fellow heads took a dim view.  The book begs so many questions, not the least educational and how and what we learn and develop.

Sir Anthony Seldon, (Vice-Chancellor, The University of Buckingham) 

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